International Niemann–Pick Disease Alliance

Active studies that are enrolling patients

 

Disease Study Drug Route Sponsor Trial Name Sites Enrolling Patients ClinicalTrials.gov Ref. No. Contact for Enrollment Questions
Niemann Pick Type C Nizubaglustat / AZ-3102 Oral Azafaros A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of Niemann-Pick Type C Disease (NPC) 30 clinical trial sites including: Argentina, Australia, Brazil, Canada, Germany, India, Italy, Portugal, Spain, Switzerland, Türkiye, United Kingdom, USA (see ClinicalTrials.gov for details) NCT07082725 info@azafaros.com
www.azafaros.com
ASMD Olipudase alfa IV Sanofi A Real-world Long-term Safety and Immunogenicity Study of Olipudase Alfa Therapy in Pediatric Patients Less Than 2 Years of Age With Acid Sphingomyelinase Deficiency (ASMD) The 5 U.S. sites are located in:

  • Chicago, Illinois
  • Cincinnati, Ohio
  • Columbus, Ohio
  • Philadelphia, Pennsylvania
  • Austin, Texas
NCT06192576 contact-us@sanofi.com

Further resources to understand clinical trials and drug development:

What patients need to know about clinical trials – resource from the FDA https://www.fda.gov/patients/clinical-trials-what-patients-need-know/basics-about-clinical-trials

The drug development process – resource from the FDA https://www.fda.gov/patients/learn-about-drug-and-device-approvals/drug-development-process

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